DR RODNEY OUELLETTE, Président et directeur scientifique :: Institut atlantique de recherche sur le cancer

En plus de participer activement à des initiatives de recherche sur le cancer et de créer des partenariats stratégiques, Dr Ouellette publie régulièrement des communications et des articles scientifiques.

Publications

23) Arseneau JR, Laflamme M, Lewis SM, Maïcas E, Ouellette RJ.(2009) Multiple isoforms of PAX5 are expressed in both lymphomas and normal B-cells. Br J Haematol. 2009 Nov;147(3):328-38. Epub 2009 Sep 1.

22) M. Cuperlovic-Culf, N. Belacel, A.S. Culf, I.C. Chute, R.J. Ouellette, I.W. Burton, T.K. Karakach, J.A. Walter “NMR metabolic analysis of samples using fuzzy K-means clustering” Magn. Reson. Chem. 47, (2009) Accepted and In press.

21) Adrian S. Culf, Ulrike Werner-Zwanziger, Katherine N. Robertson, Banghao Chen, Miroslava Cuperlovic-Culf, David A. Barnett and Rodney J. Ouellette. Polymeric and polymer-ligated spirobicyclic zwitterionic Janovsky complexes. Tetrahedron Letters : Volume 50, Issue 23, 10 June 2009, Pages 2762-2766

20) A.S. Culf*, M. Cuperlovic-Culf, R.J. Ouellette. “Chemical Exchange in Novel SpiroBicyclic Zwitterionic Janovsky Complexes using Dynamic 1H NMR Spectroscopy” Magnetic Resonance in Chemistry. 47(2), 158-164 (2009)

19) Robichaud GA, Perreault JP, Ouellette RJ. Development of an isoform-specific gene suppression system: the study of the human Pax-5B transcriptional element. Nucleic Acids Res. 2008 Aug;36(14):4609-20. Epub 2008 Jul 10.

18) Culf, C A., Laflamme, M. Cuperlovic-Culf., M Ouellette, R.J. Fast Deprotection of Synthetic Oligodeoxyribonucleotides using Standard Reagents under Microwave Irradiation. Oligonucleotides 2007 (Accepted)

17) Lucier, J.F., Bergeron, L.J., Brière, F.P., Ouellette R.J., Abou Elela, S and Perreault, J.P. RiboSubstrates: a web application addressing the cleavage specificities of ribozymes in designated genomes. BMC Bioinformatics 2006 7:480

16) Cuperlovic-Culf., M., Belacil, N., Culf, A., and Ouellette, R.J. Microarray Analysis of Alternative Splicing. Omics. 2006 10(3):344-57

15) Culf, A., Ouellette, R.J. and Cuperlovic-Culf., M. Carbohydrate Microarrays - Survey of Fabrication Techniques. Omics 2006 10(3):289-310

14) Cuperlovic-Culf, M., Culf, A.S., Laflamme, M., Ouellette, R.J., and Westcott S.A. Genomic analysis of the effects of boron compounds on a cell. Laboratory Focus 2006 10 (5), 8-9.

13) Cuperlovic-Culf., M., Belacil, N., Culf, A., and Ouellette, R.J. Data Analysis of Alternative Splicing Microarrays. Drug Discovery Today. 2006 11(21-22):983-90

12) Sonier, B., Arseneault, M., Lavigne,C., Ouellette, R.J., Vaillancourt, C. The 5-HT2A serotoninergic receptor is expressed in the MCF7 human breast cancer cell line and reveals a mitogenic effect of serotonin. Biochemical and Biophysical Research Communications. 2006 343(4):1053-9.

11) Lanoix, D., Ouellette R.J., and Vaillancourt, C. Expression of melatoninergic receptors in human placental choriocarcinoma cell lines. Human Reproduction. 2006 21(8):1981-9

10) Tao, T., Robichaud, A., Nadeau, S., Savoie, R., Gallant, B. and Ouellette, R.J. Optimisation of human oocytes for IVF and ICSI by hormonal stimulation and removal of cumulus cells. Journal of Assisted Reproduction and Genetics. 2006 23(1):23-8

9) Blacquiere, J.M., Sicora, O., Vogels, C.M., Cuperlovic-Culf, M. Decken, A., Ouellette, R.J. and Westcott, S.A. Dihydropyrimidinones containing boronic acids. Canadian Journal of Chemistry. Canadian Journal of Chemistry 83: 2052–2059 (2005)

8) Cuperlovic-Culf, M., Belacel, N., and Ouellette, R.J. Gene Selection in the Application of Microarrays in Tumour Diagnosis and Prognosis Drug Discovery Today. 10:429-37 (2005)

7) Sonier, B., Lavigne, C., Arseneault, M., Ouellette, R.J. and Vaillancourt, C. Expression of the 5-HT2A serotoninergic receptor in human placenta and choricocarcinoma cells: Mitogenic implications of serotonin. Placenta. 26:484-90. (2005)

6) Robichaud, G.A., Nardini, M., Laflamme, M. and Ouellette, R.J. Human Pax-5 C-terminal isoforms possess distinct transactivation properties and are differentially modulated in normal and malignant B cells. Journal of Biological Chemistry 279, 49956-49963 (2004)

5) Ouellette, R.J., Richard, D. and Maicas E. RT-PCR for Mammaglobin genes, MGB1 and MGB2, identifies breast cancer micrometastases in sentinel lymph nodes. American Journal of Clinical Pathology 121: 637-643 (2004)

4) Belacil, N., Cuperlovic-Culf., M., Laflamme, M., and Ouellette, R.J. Fuzzy J-means and VNS methods for clustering genes from microarray data. Bioinformatics 20: 1-20 (2004).

3) Belacil, N., Cuperlovic-Culf, M., Ouellette, R.J., and Boulassel, M.R. The Variable Neighborhood Search Metaheuristic for Fuzzy Clustering cDNA Microarray Gene Expression Data. IASTED Proceedings on Artificial Intelligence and Applications 51-57 (2004).

2) Tao, T., Robichaud, A.,Nadeau, S., Savoie, R., Gallant, B. and Ouellette, R.J. Effect of cumulus cell removal on the fertilization and the day 3 embryo quality in human IVF International Congress Series 1271, 135 - 138. (2004)

1) Cuperlovic-Culf, M., Robichaud, G.A., Nardini, M. and Ouellette, R.J. Theoretical functional analysis of Pax-5 isoforms. In Silico Biology 3: 453-469 (2003).

A.S. Culf,M. Cuperlovic-Culf, R.J Ouellette “Interesting ¹H NMR Chemical Exchange Observed in Nitro SpiroBicyclic Zwitterionic Meisenheimer Complexes” 92^nd Canadian Chemistry Conference and Exhibition. May 30 – June 3, 2009, Hamilton, ON.

A.S. Culf,M. Cuperlovic-Culf, M. Laflamme, B.J. Tardiff, R.J. Ouellette, “Fast Deprotection of Synthetic Oligodeoxyribonucleotides using Standard Reagents under Microwave Irradiation” 92^nd Canadian Chemistry Conference and Exhibition. May 30 – June 3, 2009, Hamilton, ON.

A.S. Culf, U. Werner-Zwanziger, K.N. Robertson, B.Chen, M. Cuperlovic-Culf, D.A. Barnett, R.J. Ouellette ^“Polymeric and polymer-ligated SpiroBicyclic Zwitterionic Janovsky complexes” 92^nd Canadian Chemistry Conference and Exhibition. May 30 – June 3, 2009, Hamilton, ON.